International Collaborative Partner of UTAR Global Research Network



Name Prof Dr Thomas J Smith
Designation Professor
Qualification PhD, Cell and Molecular Biology, University of Edinburgh, UK, 1992.
MA, University of Cambridge, 1991.
BA, Natural Sciences (Biochemistry), University of Cambridge, UK, 1987.
Organization Biomedical Research Centre, Sheffield Hallam University
Email t.j.smith@shu.ac.uk
Tel No. +44 (0) 144 225 3042
Fax No. +44 (0) 144 225 3066
URL http://www.shu.ac.uk/research/bmrc/sp_tom_smith.html
UTAR Contact Person Dr Alan Ong Han Kiat, onghk@utar.edu.my


Employment
  • Principal Lecturer in Microbiology, Sheffield Hallam University, UK, 2001 to current.
  • Postdoctoral Research Associate, Department of Biological Sciences, University of Warwick, UK, 1996-2001.
  • Postdoctoral Research Associate, Department of Molecular Biology and Biotechnology, University of Sheffield, UK, 1993-1996.
  • Postdoctoral Research Associate, Centre for Advanced Research in Biotechnology, Rockville, MD, USA, 1993.
Teaching Interests
  • Microbial biotechnology
  • Enzymology
  • Bioinformatics
Research Interests
  • Bacterial oxygenases, enzymology and applied microbiology
  • Protein engineering of bacterial oxygenases
  • Microbiology of aquaculture
  • New expression systems for biocatalysts
  • Novel antimicrobial agents from natural products
  • Microbiological applications in materials science
  • Use of molecular microbiology techniques to study microorganisms in hospitals
Publications & Presentation
  • He has published more than 25 articles in the form of international journals and over 50 outputs in the form of book chapter, conference paper, research reports etc.
Awards & Honors
  • Awarded one of four 'promising researcher fellowships' at Sheffield Hallam University (2005-7).
Professional Activities
  • International and national presentations in research seminars e.g. NRCC Montreal (1999), Warwick (2004), Katowice (2004), Tsinghua University Beijing (2007), UTAR Kuala Lumpur (2007).
  • Invited speakers e.g. Gordon Research Conference in New London (Connecticut, USA), 2002.
  • Oral presentation at Biotrans 2007 in Oviedo, Spain, 2007.
  • Editorial board of Journal of Applied Microbiology and Letters in Applied Microbiology, since 2005.
  • Peer reviewing of papers and grant applications.
Professional Membership
Society for General Microbiology; Society for Applied Microbiology; Biochemical Society.

Funded Research Projects
Laboratory evolution of alkene monooxygenase for improved chiral synthesis, BBSRC (ref. E20252), £209k, 2003-2007.
Exploring the catalytic versatility of soluble methane monooxygenase, BBSRC (ref. BB/C00399X/1), with J.C. Murrell (University of Warwick). £119k for Sheffield Hallam based part of project, 2004-2007.
Development of an affinity purification protocol for alkene monooxygenase, Society for General Microbiology, £1.7k, Summer 2004.
Development of a unifying technology for enantioselective and regioselective biocatalysis, BBSR China Partering award (ref. PA1519), with J.C. Murrell (University of Warwick) and M-H. Zong and co-workers (South China University of Technology), £15.1k, 2005-2009.
Investigation of heterologous expression of alkene monooxygenease in a methylotrophic bacterium, Society for General Microbiology £1.4k, Summer 2005.
Detection of volatile organic compounds using novel biocatalyst/so gel based biosensors, Medical Research Discipline Hopping Award, with R. Akid (Sheffield Hallam University), £84,522, 2006-2007
Characterisation of novel antimicrobial peptides produced by scorpions from India, Society for General Microbiology, £1760, 2006-2007
Molecular microbiology and antibiotic resistance in the ICU environment: can molecular audit inform clinical management?. PhD student funded jointly by Sheffield Hallam University, AstraZeneca PLC, Astellas PLC and Pfizer PLC. In collaboration with K. Stanley (Sheffield Hallam) and G. Mills, R. Townsend, D. Edbrooke, S.T. Green (Sheffield Teaching Hospitals NHS trust), 2006-9.
Investigation of a possible gating residue at the mouth of the active site of alkene monooxygenase, Society for General Microbiology, £1760, Summer 2007.
Development of a function sol gel coating system via encapsulation of microorganisms, EPSRC (ref.EP/F008643/1) with R. Akid (PI, Materials and Engineering Research Institute, Sheffield Hallam University), £354,638, 2007-2010.
'Molecular microbiology of a combined farmed freshwater fish and hydroponic system: toward coupled sustainable fish and food plant production', British Council (PMI2). Dr Alan Ong (Universiti Tunku Abdul Rahman, Malaysia). £14,226, 2008-2010.
'Promoting commercial uptake of monooxygenase biocatalysts', Bioscience for Business Knowledge Transfer Network, FROPTOP and CoEBio3. £12,500, 2008-2009.
'Novel monooxygenase biocatalysts from the environment and the laboratory', BBSRC (ref. BB/F01449X/1); with J. C. Murrell (University of Warwick). £293,905, 2008-2011.

Quarterly Activites
April - June 2018
  • Discussion on NGS and miRNA extraction from patient blood and sampling strategy for PhD proposal on Prebiotics and probiotics of IBD for a potential PhD candidate.
January - March 2018
  • Discussion on PhD proposal on Prebiotics and probiotics of IBD for a potential PhD candidate.
October - December 2017
  • To provide feedback on finalised PhD proposal on Prebiotics and probiotics of IBD for a potential PhD candidate.
July - September 2017
  • Planing a PhD proposal for a potential PhD candidate on the area of Prebiotics and Probiotics for bowel diseases
April - June 2017
  • Writing a paper of a master student's project on metagenomics bacteria diveristy in edible best nests and initiating master student's research work.
January - March 2017
  • Planning on writing a paper of a master student's project on metagenomics bacteria diveristy in edible best nests.
October - December 2016
  • Planning on a potential Phd candidate proposal in the areas of medical microbiology
July - September 2016
  • Providing inputs and technical advice on Microbial Diversity of a Masters Student thesis and paper writing
April - June 2016
  • Providing inputs and technical advice on Microbial Diversity of a Masters Student thesis
January - March 2016
  • Planning out a joint PhD supervision for a potential dual PhD program / candidate
October - December 2015
  • Pass through the initial round on Joint grant application - Newton Links Grant
July - September 2015
  • Joint grant application - Newton Links Grant
April - June 2015
  • A joint scientific paper manuscript on a research study on bacteria diversity in aquaculture (larvea culture) under the PMI2 and UTARRF grant is pending submission into a ISI indexed journal (in progress)
  • Appointment as an External Examinser for a Masters thesis (in progress)
January - March 2015
  • A joint scientific paper manuscript on a research study on bacteria diversity in aquaculture (larvea culture) under the PMI2 and UTARRF grant is pending submission into a ISI indexed journal (in progress)
  • Appointment as an External Examinser for a Masters thesis (in progress)
October - December 2014
  • A joint scientific paper manuscript on a research study on bacteria diversity in aquaculture (larvea culture) under the PMI2 and UTARRF grant is pending submission into a ISI indexed journal
  • Appointment as an External Examinser for a Masters thesis
July - September 2014
  • No activity
April - June 2014
  • A joint scientific paper manuscript on a research study on bacteria diversity in disused mining ponds in Kampar under MTSF grant has been accepted by World Journal of Microbiology and Biotechnology (ISI indexed)
January - March 2014
  • Another joint scientific paper manuscript on a research study involving MTSF grant has been submitted and awaiting review results by the journal.
October - December 2013
  • Joint paper on a research study involving MTSF grant was accepted in World Journal of Microbiology and Biotechnology in September
  • Preparation for another joint scientific paper manuscript on a research study involving MTSF grant is currently in progress
July - September 2013
  • Joint paper manuscript on a research study involving MTSF grant to be submitted for publication
  • Renewal of ICP appointment
  • Sourcing of External Examiner for a Post graduate thesis report
April - June 2013
  • Joint paper manuscript on a research study involving MTSF grant to be submitted for publication
  • Renewal of ICP appointment
  • Sourcing of External Examiner for a Post graduate thesis report
January - March 2013
  • Joint paper manuscript on a research study involving MTSF grant to be submitted for publication
October - December 2012
  • Joint paper manuscript writing in progress for a research study involving MTSF grant.
  • Appointed as an External Examiner for an MSc Candidiate
July - September 2012
  • Joint paper manuscript writing in progress for a research study involving MTSF grant.
April - June 2012
  • Jointly publishing research studies associated with the PMI2 grant - Paper accepted in "The Israeli Journal of Aquaculture – Bamidgeh" (An ISI index journal)
January - March 2012
  • Jointly publishing research studies associated with the PMI2 grant - pending review results
October - December 2011
  • Jointly publishing research studies associated with the PMI2 grant. A second paper has been submitted to Journal of Applied Aquaculture, pending review results
July - September 2011
  • Jointly publishing research studies associated with the PMI2 grant. One paper entitled "Highly Unsaturated Fatty Acid (HUFA) Retention Quality in Freshwater Cladoceran, Moina macrocopa, Enriched With Lipid Emulsions" has recently been accepted in the Israeli Journal of Aquaculture – Bamidgeh (ISSN 0792 – 156X)
April - June 2012
  • Assisting in paper writing for publication. Commenced in May 2011. Research project under PMI2 grant (British Council)
January - March 2011
  • No activity
October - December 2010
  • Post Graduate Student Attachment, Mr Tan Eng Teik at SHU research lab on 14th -29th Nov 2010 (Travelling and accomodation expenses paid by PMI2 grant)
July - September 2010
  • 1 week exchange visit (20-26/7/10)
  • Student exchange (20/7-13/9/10)
  • General Talk entitled "Aquaculture and molecular microbiology toward a safe and sustainable future” (21/7/10)
  • Research site visit at disused tin mining ponds at Perak Campus
April - June 2010
  • Planning of exchange visit by Dr Thomas Smith and the student exchange in FMHS (Sg. Long) and FS (Kampar), RM12 grant
    • Participant: Mr Patrick Liam
January - March 2010
  • Poster presentation in a Conference under the Society for General Microbiology Spring Conference EICC. Title of the Paper "Molecular microbiology of farmed freshwater fish: toward coupled sustainable fish and food plant production" 29 March - 1 April, 2010. Edinburgh, UK, RM12 grant
    • Participant: E. T. Tan , C. S. Tan , Dr Gideon Khoo , Mr Jiun Yan Loh, Dr Alan Ong and Dr Malcolm Lock.
September - December 2009
  • Co-author and sponsor of a UTAR MSc student's poster presentations (2 posters) in the Asian Pacific Aquaculture 2010 Seminar organised by World Aquaculture Society. 3-6 November, 2009. KL, RM12 grant
    • Members: Mr Loh Jiun Yan / Hii Yii Siang , Dr Alan Ong, Dr Malcolm Lock, Dr Thomas J. Smith and Dr Gideon Khoo
  • Hosted a MSc Student for a 3- months research attachment in his lab at the Biomedical Research Centre, Faculty of Health & Wellbeing, Sheffield Hallam University, United Kingdom, April - June 2009, PMI2 grant
    • Participant: Mr. Loh Jiun Yan
  • Hosted a 1-week research visit to the Biomedical Research Centre, Faculty of Health & Wellbeing, Sheffield Hallam University, United Kingdom, Apr-09, PMI2 grant
    • Participant: Dr. Alan Ong